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HIV/AIDS Clinical Care

Journal Watch condenses summaries of key research across specialties from more than 250 medical journals into concise yet comprehensive articles, incorporating clinical commentary from prominent physician-editors in the field.


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Featured Article

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SUMMARY AND COMMENT

Preventing HBV Infection with ARTFree

Antiretroviral regimens containing 3TC, tenofovir, or both, reduced the risk for incident hepatitis B virus infection by approximately 90% compared with other or no antiretrovirals.

Recent HIV/AIDS Clinical Care Articles

SUMMARY AND COMMENT

Functional Impairment in HIV-Infected Patients

In patients on suppressive antiretroviral therapy, greater CD8-cell activation and higher interleukin-6 level are associated with functional impairment.

FEATURE

ID Learning Unit — "Isolator" Blood CulturesFree

In his blog HIV and ID Observations, Dr. Paul Sax explains the indications for an obscure blood test used by ID consultants.

SUMMARY AND COMMENT

Another Step Toward Eliminating HIV Infection?Free

In two patients, allogeneic stem-cell transplantation under the cover of ART produced sustained reduction of HIV reservoirs in peripheral blood mononuclear cells.

SUMMARY AND COMMENT

Major Decline in CD4-Cell Count in Virally Suppressed Patients Signals Threat to Health

In a cohort of HIV-infected patients on ART with suppressed viral load, sustained CD4-cell count declines were associated with increased risk for morbidity and death.

SUMMARY AND COMMENT

In Some Areas, Lipodystrophy Afflicts Most ART Recipients

A study conducted in France found that more than 80% are affected.

FEATURE

ID Learning Unit — Antibiotics with Excellent Oral AbsorptionFree

In his blog HIV and ID Observations, Dr. Paul Sax makes the case for oral antibiotics.

SUMMARY AND COMMENT

Predictors of Response to Second-Line Therapy — Do the NRTIs Matter?Free

A retrospective analysis suggests that treatment failure on a second-line regimen is as common with one or more new nucleoside reverse-transcriptase inhibitors as with none.

SUMMARY AND COMMENT

Incident HCV Infection in MSM

Hepatitis C virus infection has occurred among men who have sex with men since the beginning of the HIV epidemic, with higher rates of infection among those who are HIV-infected.

GUIDELINE WATCH

HIV Opportunistic Infection Guidelines, Updated

These guidelines, last revised in 2009, are comprehensive, exhaustively referenced, and authoritative.

FEATURE

FDA: Fecal Transplants Need Investigational New Drug ApplicationFree

In his blog HIV and ID Observations, Dr. Paul Sax weighs in on a recent FDA decision regarding fecal microbiota transplantation.

Browse our complete HIV/AIDS Clinical Care archive >>

Journal Watch HIV/AIDS Clinical Care summarizes important medical journal articles about a wide variety of HIV-related subjects including acute HIV infection, antiretroviral resistance, epidemiology, hepatitis, initial therapy, medication adherence, opportunistic infections, and STDs.

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Aids Clinical Care Editor-in-Chief

HIV/AIDS Journal Watch
Paul E. Sax, MD
Clinical Director, HIV Program and Division of Infectious Diseases, Brigham and Women's Hospital

More about Journal Watch HIV/AIDS and its board >>

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