Search for Acute Infection in HIV/AIDS Clinical Care

Physician-authored summaries on the latest research on acute infection, editorials on acute infection, and perspectives on acute infection - drawn from the top medical journals.

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You searched for: acute infection in HIV/AIDS

Nucleic-Acid Amplification Testing Might Improve Detection of Acute Infection
- May 11, 2005
- Charles B. Hicks, MD
- HIV/AIDS
Adding nucleic-acid testing to standard antibody testing improved the detection of acute HIV infection in North Carolina — and was cost-effective.
- Reviewing:
- Pilcher CD et al., N Engl J Med 2005 May 5; 352:1873-83.
- Related Searches: hiv, hiv infection syndrome, acute, hiv screen, nucleic acid amplification tests
Massive CD4+ T cell Depletion in Acute Infection
- April 13, 2005
- Timothy Lahey, MD
- HIV/AIDS
Two animal studies document massive and rapid depletion of CD4+ memory T cells in the blood and intestinal mucosa during acute infection.
- Reviewing:
- Mattapallil JJ et al., Nature 2005 Mar 27;: Li Q et al., Nature 2005 Mar 27;:
- Related Searches: cd4 count determination procedure, hiv, hiv infection syndrome, acute
No Clear Benefit of Antiretroviral Therapy for Acute Infection: More Evidence
- February 1, 2005
- Keith Henry, MD
- HIV/AIDS
Comparison of treated versus untreated patients identified during acute infection found no significant difference in viral loads an estimated 36 months after infection.
- Reviewing:
- Desquilbet L et al., AIDS 2004 Dec 3; 18:2361-9.
- Related Searches: anti-retroviral agents, drug holiday, hiv, hiv infection syndrome, acute, viral load result
High Semen HIV Levels During Acute Infection May Shape Epidemic
- August 1, 2004
- Abigail Zuger, MD
- HIV/AIDS
During acute HIV infection, high semen levels of the virus make men "biologically hyperinfectious;" a sizeable fraction of sexual transmission of HIV may take place during this time.
- Reviewing:
- Pilcher CD et al., J Infect Dis 2004 May 15; 189:1785-92.
Untangling the Sequence of Events in Acute Infection
- November 1, 2003
- Deborah J. Cotton, MD, MPH
- HIV/AIDS
Researchers examined samples from blood donors with acute infection to determine which tests show what and when.
Risk for Vertical Postpartum HIV Transmission During Acute Infection
- August 24, 2009
- Sonia Nagy Chimienti, MD
- HIV/AIDS
In a retrospective case series of women who acquired HIV from postpartum blood transfusions, the absolute risk for transmitting HIV vertically through breast-feeding was 36%.
- Reviewing:
- Liang K et al., J Infect Dis 2009 Sep 1; 200:682. Lockman S and Creek T., J Infect Dis 2009 Sep 1; 200:667.
- Related Searches: breast feeding, hiv, hiv transmission, postpartum infection, vertical disease transmission
Identifying Patients with Acute HIV Infection and Their Partners
- August 10, 2009
- Sonia Nagy Chimienti, MD
- HIV/AIDS
In North Carolina, a protocol for negative or indeterminate HIV-antibody results that involved nucleic acid amplification testing, confirmatory antibody testing, and follow-up interviews led to identification of newly infected partners of newly infected patients.
- Reviewing:
- Moore ZS et al., J Acquir Immune Defic Syndr 2009 Jun 26;:
- Related Searches: hiv, hiv screen, hiv-1 antibody assay, nucleic acid amplification tests, sexual partners
Stuck in the Middle Free
- July 27, 2009
- HIV/AIDS
A clinician sustains a needlestick from a patient who refuses HIV testing. An HIV physician, an attorney, and an ethicist weigh provide weigh in on how best to manage.
- Related Searches: hiv postexposure prophylaxis, hiv screen, needlestick injuries, refusal of consent
Which HIV Test Is Best in High-Incidence Groups?
- July 27, 2009
- Carlos del Rio, MD
- HIV/AIDS
In a study of specimens from Seattle-area MSM, a rapid antibody test detected HIV infection less well than did either enzyme immunoassay antibody testing or nucleic-acid amplification testing.
- Reviewing:
- Stekler JD et al., Clin Infect Dis 2009 Aug 1; 49:444.
- Related Searches: enzyme immunoassay, hiv, hiv screen, male homosexuality, nucleic acid amplification tests, oraquick rapid hiv-1 antibody test
HIV Testing — Targeting High-Risk Populations
- June 1, 2009
- Charles B. Hicks, MD
- HIV/AIDS
In an innovative program of bathhouse-based HIV testing, 4% of participants were found to be HIV-infected.
- Reviewing:
- Daskalakis D et al., Clin Infect Dis 2009 Jun 1; 48:1609.
- Related Searches: hiv, hiv screen, male homosexuality, rapid hiv test
What Happens When PEP or PrEP Fails?
- September 29, 2008
- Raphael J. Landovitz, MD
- HIV/AIDS
A case report provides at least some reassurance that failure of antiretroviral prophylaxis does not necessarily result in drug resistance.
- Reviewing:
- Prada N et al., J Acquir Immune Defic Syndr 2008 Sep 2;:
- Related Searches: anti-retroviral agents, drug resistance, emtricitabine, hiv, hiv postexposure prophylaxis, hiv prevention, tenofovir, tenofovir/emtricitabine
Continued Problems with Late HIV Diagnosis and New Problems with Testing Scale-Up
- March 10, 2008
- Carlos del Rio, MD
- HIV/AIDS
Several reports presented at the 15th Retrovirus Conference highlighted ongoing challenges with HIV testing.
- Related Searches: acquired immunodeficiency syndrome, anti-retroviral agents, hiv, hiv screen
Limitations of Rapid Testing Free
- July 16, 2007
- Rochelle P. Walensky, MD, MPH
- HIV/AIDS
The performance characteristics of a sequential rapid HIV-testing algorithm were poorer than anticipated in a Ugandan study, perhaps due to false-positive results from tests with “faint bands.”
- Reviewing:
- Gray RH et al., BMJ 2007 Jun 1;:
- Related Searches: hiv, hiv screen, rapid hiv test, uganda
Primary HIV Infection — Predicting the Set Point Free
- June 18, 2007
- Charles B. Hicks, MD
- HIV/AIDS
Having a greater number of symptoms during primary infection was associated with a higher initial viral load, which, in turn, was associated with a higher viral set point.
- Reviewing:
- Kelley CF et al., J Acquir Immune Defic Syndr 2007 May 17;:
- Related Searches: hiv, hiv infection, primary, hiv infection, symptomatic, viral load result
A Single Case of Patient-to-Patient HBV Transmission in an Oral Surgery Center
- May 14, 2007
- Rachel Baden, MD
- HIV/AIDS
The case occurred despite apparent adherence to standard infection control measures and vaccination of nearly all healthcare personnel.
- Reviewing:
- Redd JT et al., J Infect Dis 2007 May 1; 195:1311-4. Allos BM and Schaffner W., J Infect Dis 2007 May 1; 195:1245-7.
- Related Searches: disease transmission, hepatitis b, hepatitis b virus, hiv
Resistance Testing: A New Emphasis on Detecting Transmitted Resistance Free
- December 29, 2006
- HIV/AIDS
All HIV-infected patients should undergo genotype testing prior to initiation of antiretroviral therapy.
- Related Searches: anti-retroviral agents, CASCADE, drug resistance, hiv, hiv and pregnancy, hiv screen, reverse transcriptase inhibitors, zidovudine
Improving Diagnosis of Acute HIV Infection
- December 18, 2006
- Charles B. Hicks, MD
- HIV/AIDS
A growing body of evidence supports the use of nucleic-acid amplification testing to improve diagnosis of acute infection.
- Reviewing:
- Truong HH et al., AIDS 2006 Nov 14; 20:2193-7. Priddy FH et al., J Acquir Immune Defic Syndr 2006 Nov 30;:
- Related Searches: hiv, hiv infection syndrome, acute, hiv screen, hiv transmission, nucleic acid amplification tests, rapid hiv test
Treatment of Acute HIV Infection
- October 2, 2006
- G. Sonia Nagy, MD
- HIV/AIDS
Two small, nonrandomized studies fall short of providing clear answers about whether to initiate potent combination antiretroviral therapy at a very early stage of infection.
- Reviewing:
- Hecht FM et al., J Infect Dis 2006 Sep 15; 194:725-33. Streeck H et al., J Infect Dis 2006 Sep 15; 194:734-9. Kinloch-de Loes S., J Infect Dis 2006 Sep 15; 194:721-4.
- Related Searches: anti-retroviral agents, hiv, hiv infection syndrome, acute, lamivudine, lamivudine/zidovudine, lopinavir, lopinavir/ritonavir, ritonavir, zidovudine
DHHS Treatment Guidelines Updated
- May 10, 2006
- Abigail Zuger, MD
- HIV/AIDS
New HIV treatment guidelines include updates on genotypic resistance testing and treatment interruptions.
- Reviewing:
- ,;:
- Related Searches: anti-retroviral agents, assay, genotype, hiv drug resistance, in vitro, drug holiday, drug resistance, viral, hiv
Transmitted Resistance in the CASCADE Collaboration
- January 4, 2006
- Charles B. Hicks, MD
- HIV/AIDS
Transmitted HIV-drug resistance appears to have increased over time in a large cohort from Europe and Canada, but what actually constitutes significant antiretroviral drug resistance?
- Reviewing:
- Masquelier B et al., J Acquir Immune Defic Syndr 2005 Dec 15; 40:505-11.
- Related Searches: anti-retroviral agents, CASCADE, drug resistance, hiv

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Search for Acute Infection in HIV/AIDS Clinical Care

Nucleic-Acid Amplification Testing Might Improve Detection of Acute Infection

Massive CD4+ T cell Depletion in Acute Infection

No Clear Benefit of Antiretroviral Therapy for Acute Infection: More Evidence

High Semen HIV Levels During Acute Infection May Shape Epidemic

Untangling the Sequence of Events in Acute Infection

Risk for Vertical Postpartum HIV Transmission During Acute Infection

Identifying Patients with Acute HIV Infection and Their Partners

Stuck in the Middle Free

Which HIV Test Is Best in High-Incidence Groups?

HIV Testing — Targeting High-Risk Populations

What Happens When PEP or PrEP Fails?

Continued Problems with Late HIV Diagnosis and New Problems with Testing Scale-Up

Limitations of Rapid Testing Free

Primary HIV Infection — Predicting the Set Point Free

A Single Case of Patient-to-Patient HBV Transmission in an Oral Surgery Center

Resistance Testing: A New Emphasis on Detecting Transmitted Resistance Free

Improving Diagnosis of Acute HIV Infection

Treatment of Acute HIV Infection

DHHS Treatment Guidelines Updated

Transmitted Resistance in the CASCADE Collaboration

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