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Acute Infection
Physician-authored summaries on the latest research on acute infection, editorials on acute infection, and perspectives on acute infection - drawn from the top medical journals.
You searched for: acute infection Items 1 to 20 of 52 results
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Massive CD4+ T cell Depletion in Acute Infection
- April 13, 2005
- Timothy Lahey, MD
Two animal studies document massive and rapid depletion of CD4+ memory T cells in the blood and intestinal mucosa during acute infection.- Covering:
- Mattapallil JJ et al., Nature 2005 Mar 27;:
- Li Q et al., Nature 2005 Mar 27;:
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No Clear Benefit of Antiretroviral Therapy for Acute Infection: More Evidence
- February 1, 2005
- Keith Henry, MD
Comparison of treated versus untreated patients identified during acute infection found no significant difference in viral loads an estimated 36 months after infection.- Covering:
- Desquilbet L et al., AIDS 2004 Dec 3; 18:2361-9.
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Untangling the Sequence of Events in Acute Infection
- November 1, 2003
- Deborah J. Cotton, MD, MPH
Researchers examined samples from blood donors with acute infection to determine which tests show what and when. -
Nucleic-Acid Amplification Testing Might Improve Detection of Acute Infection
- May 11, 2005
- Charles B. Hicks, MD
Adding nucleic-acid testing to standard antibody testing improved the detection of acute HIV infection in North Carolina — and was cost-effective.- Covering:
- Pilcher CD et al., N Engl J Med 2005 May 5; 352:1873-83.
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High Semen HIV Levels During Acute Infection May Shape Epidemic
- August 1, 2004
- Abigail Zuger, MD
During acute HIV infection, high semen levels of the virus make men "biologically hyperinfectious;" a sizeable fraction of sexual transmission of HIV may take place during this time.- Covering:
- Pilcher CD et al., J Infect Dis 2004 May 15; 189:1785-92.
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Improving Diagnosis of Acute HIV Infection
- December 18, 2006
- Charles B. Hicks, MD
A growing body of evidence supports the use of nucleic-acid amplification testing to improve diagnosis of acute infection.- Covering:
- Truong HH et al., AIDS 2006 Nov 14; 20:2193-7.
- Priddy FH et al., J Acquir Immune Defic Syndr 2006 Nov 30;:
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Treatment Interruption: Still in Search of a Niche
- December 28, 2005
Treatment interruption is not recommended during acute infection or salvage therapy. Its potential role during chronic infection, however, is still being determined. -
Routine Screening for Acute HIV
- October 1, 2002
- Helmut Albrecht, MD
Routine screening at a state-funded laboratory detected previously undiagnosed long-standing HIV infection in 39 of 8194 serum samples. Viral-load testing of batched specimens detected acute infection in 4 additional patients. -
The Best Way to Diagnose Acute HIV Infection
- March 1, 2001
- Abigail Zuger, MD
Viral load and p24 antigen assays each have advantages and drawbacks in the diagnosis of acute infection. -
Before Seroconversion: The Clinical and Scientific Events of Acute HIV Infection and the Immunologic Benefits of Treatment
- January 1, 2001
- Judith Currier, MD, MSc
Recent evidence suggests that the timely diagnosis and effective management of acute infection may have important immunologic, virologic, and clinical implications for the subsequent course of HIV disease in infected patients. Recent studies have suggested that initiating antiretroviral treatment during acute infection may allow for the development of critical immune responses that may make it possible for individuals ultimately to discontinue therapy and achieve immunologic control of the virus. -
More on Oral Sex and HIV Transmission Risk
- December 1, 2003
- G. Sonia Nagy, MD
Detailed interviews of a cohort of gay men with acute infection provide further evidence that oral sex can be a route of HIV transmission and suggest that penile piercings may increase this risk. -
Continued Problems with Late HIV Diagnosis and New Problems with Testing Scale-Up
- March 10, 2008
- Carlos del Rio, MD
Several reports presented at the 15th Retrovirus Conference highlighted ongoing challenges with HIV testing. -
Limitations of Rapid TestingFree!
- July 16, 2007
- Rochelle P. Walensky, MD, MPH
The performance characteristics of a sequential rapid HIV-testing algorithm were poorer than anticipated in a Ugandan study, perhaps due to false-positive results from tests with “faint bands.”- Covering:
- Gray RH et al., BMJ 2007 Jun 1;:
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Primary HIV Infection — Predicting the Set PointFree!
- June 18, 2007
- Charles B. Hicks, MD
Having a greater number of symptoms during primary infection was associated with a higher initial viral load, which, in turn, was associated with a higher viral set point.- Covering:
- Kelley CF et al., J Acquir Immune Defic Syndr 2007 May 17;:
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A Single Case of Patient-to-Patient HBV Transmission in an Oral Surgery Center
- May 14, 2007
- Rachel Baden, MD
The case occurred despite apparent adherence to standard infection control measures and vaccination of nearly all healthcare personnel.- Covering:
- Redd JT et al., J Infect Dis 2007 May 1; 195:1311-4.
- Allos BM and Schaffner W., J Infect Dis 2007 May 1; 195:1245-7.
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Resistance Testing: A New Emphasis on Detecting Transmitted ResistanceFree!
- December 29, 2006
All HIV-infected patients should undergo genotype testing prior to initiation of antiretroviral therapy. -
Treatment of Acute HIV Infection
- October 2, 2006
- G. Sonia Nagy, MD
Two small, nonrandomized studies fall short of providing clear answers about whether to initiate potent combination antiretroviral therapy at a very early stage of infection.- Covering:
- Hecht FM et al., J Infect Dis 2006 Sep 15; 194:725-33.
- Streeck H et al., J Infect Dis 2006 Sep 15; 194:734-9.
- Kinloch-de Loes S., J Infect Dis 2006 Sep 15; 194:721-4.
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DHHS Treatment Guidelines Updated
- May 10, 2006
- Abigail Zuger, MD
New HIV treatment guidelines include updates on genotypic resistance testing and treatment interruptions.- Covering:
- ,;:
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Transmitted Resistance in the CASCADE Collaboration
- January 4, 2006
- Charles B. Hicks, MD
Transmitted HIV-drug resistance appears to have increased over time in a large cohort from Europe and Canada, but what actually constitutes significant antiretroviral drug resistance?- Covering:
- Masquelier B et al., J Acquir Immune Defic Syndr 2005 Dec 15; 40:505-11.
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No Improvement in Virologic Control After Therapeutic Vaccination
- August 31, 2005
- Keith Henry, MD
Therapeutic vaccination did not lead to durable virologic control after treatment interruption in acutely infected individuals.- Covering:
- Kinloch-de Loes S et al., J Infect Dis 2005 Aug 15; 192:607-17.
- Gandhi RT and Altfeld M., J Infect Dis 2005 Aug 15; 192:556-9.
You searched for: acute infection Items 1 to 20 of 52 results