HIV/AIDS Clinical Care: Archives

SUMMARY AND COMMENT

More on Blood β-Glucan to Diagnose PCP

• September 28, 2009
• Paul E. Sax, MD

In a study conducted in Japan, 96% of patients with HIV-related PCP had abnormal β-glucan levels.

• Reviewing:
• Watanabe T et al., Clin Infect Dis 2009 Oct 1; 49:1128

SUMMARY AND COMMENT

Diabetes Care in HIV-Infected PatientsFree

• September 21, 2009
• Nancy Kim, MD, PhD, and Amy C. Justice, MD, PhD

In a single-center, cross-sectional study, more than half of the HIV-infected patients with diabetes met the 2008 ADA goals for hemoglobin A_1c levels, blood pressure, and lipid levels.

• Reviewing:
• Adeyemi O et al., Clin Infect Dis 2009 Sep 1; 49:799

SUMMARY AND COMMENT

Early Mortality After ART InitiationFree

• September 4, 2009
• Keith Henry, MD

In Uganda, 14% of those who started ART died within the first year, mostly from HIV-related causes; only 5% of those deaths were attributable to immune reconstitution inflammatory syndrome.

• Reviewing:
• Castelnuovo B et al., Clin Infect Dis 2009 Sep 15; 49:965 Davies MA and Meintjes G., Clin Infect Dis 2009 Sep 15; 49:973

SUMMARY AND COMMENT

ART and the Risk for Sexual HIV Transmission

• September 4, 2009
• Salim S. Abdool Karim, MD, PhD

In this study, no transmissions occurred in HIV-infected patients with viral loads <400 copies/mL on ART. However, evidence is still insufficient to estimate the risk of transmission directly or to provide guidance on the use of ART for preventing HIV transmission.

• Reviewing:
• Attia S et al., AIDS 2009 Jul 17; 23:1397

SUMMARY AND COMMENT

Maraviroc — Probably Not the Silver Bullet for Patients with Impaired CD4-Cell Recovery

• September 4, 2009
• Helmut Albrecht, MD

In a small retrospective study, maraviroc did not significantly improve CD4-cell counts in patients with discordant responses to combination antiretroviral therapy.

• Reviewing:
• Stepanyuk O et al., AIDS 2009 Sep 10; 23:1911

SUMMARY AND COMMENT

STD Screening Among MSM

• September 4, 2009
• Sonia Nagy Chimienti, MD

During a 2-year period, STD testing was performed at 23% of all MSM visits to a Boston clinic. At least one STD was diagnosed at 11% of those visits.

• Reviewing:
• Mimiaga MJ et al., Sex Transm Dis 2009 Aug; 36:507

SUMMARY AND COMMENT

Low-Level Viremia Affects Immunity in Elite Controllers

• September 4, 2009
• Abigail Zuger, MD

Higher levels of detectable virus on an ultrasensitive assay correlated with stronger antibody responses but had no relation to HIV-specific T-cell response.

• Reviewing:
• Pereyra F et al., J Infect Dis 2009 Sep 15; 200:984

MEETING REPORT

ALTAIR — The End of NRTI-Only Regimens

• August 31, 2009
• Helmut Albrecht, MD

In a randomized study, standard combination therapy was preferable to a quadruple-NRTI regimen in terms of both virologic control and adverse effects.

DRUG WATCH

Etravirine Can Cause Severe Skin and Hypersensitivity Reactions

• August 31, 2009
• Paul E. Sax, MD

Severe skin or hypersensitivity reactions should prompt immediate cessation of the drug.

• Reviewing:
• 2009

MEETING REPORT

Report from the 5th IAS Conference on HIV Pathogenesis, Treatment and PreventionFree

• August 31, 2009
• ACC Editors

Our physician-editors detail the most important findings from this year's meeting