HIV/AIDS Clinical Care: Archives

MEETING REPORT

Early ART Initiation Improves Survival in Resource-Limited SettingsFree

• August 31, 2009
• Gerald H. Friedland, MD

New findings from Haiti (described at IAS 2009) support starting ART when CD4 counts fall below 350 cells/mm³ — the same threshold that is recommended in resource-rich settings.

MEETING REPORT

Maternal ART Reduces Transmission of HIV through Breast-FeedingFree

• August 31, 2009
• Judith Feinberg, MD

In a study conducted in Botswana (and reported at IAS 2009), the rate of mother-to-child transmission was only 1% among breast-feeding women who received ART through 6 months postpartum.

MEETING REPORT

Nevirapine vs. Boosted Atazanavir — The ARTEN Study

• August 31, 2009
• Paul E. Sax, MD

The combination of nevirapine + tenofovir + FTC (or 3TC) is safe and effective in treatment-naive patients, according to data presented at IAS 2009.

MEETING REPORT

GSK572 — A "Next-Generation" Integrase Inhibitor?

• August 31, 2009
• Charles B. Hicks, MD

Early data presented at IAS 2009 are encouraging.

MEETING REPORT

Abacavir and CVD — Again

• August 31, 2009
• Paul E. Sax, MD

One large study presented at IAS 2009 supported an association between abacavir and cardiovascular risk, but another did not.

MEETING REPORT

Strategies for Antiretroviral Deintensification

• August 31, 2009
• Charles B. Hicks, MD

Data presented at IAS 2009 highlighted new approaches to PI therapy for patients with virologic suppression, including simplifying ritonavir-boosted atazanavir to unboosted atazanavir and trying to sustain suppression using darunavir without nucleosides. Success rates differed among these strategies.

SUMMARY AND COMMENT

Risk for Vertical Postpartum HIV Transmission During Acute Infection

• August 24, 2009
• Sonia Nagy Chimienti, MD

In a retrospective case series of women who acquired HIV from postpartum blood transfusions, the absolute risk for transmitting HIV vertically through breast-feeding was 36%.

• Reviewing:
• Liang K et al., J Infect Dis 2009 Sep 1; 200:682 Lockman S and Creek T., J Infect Dis 2009 Sep 1; 200:667

MEETING REPORT

Report from the XVIII International HIV Drug Resistance WorkshopFree

• August 24, 2009
• Daniel R. Kuritzkes, MD

An expert's take on the most clinically relevant reports from this year's resistance meeting

CLINICAL PRACTICE GUIDELINE WATCH

Primary Care for HIV-Infected Patients — New IDSA Guidelines

• August 24, 2009
• Charles B. Hicks, MD

The recommendations encompass both HIV-specific care and overall health maintenance.

• Reviewing:
• Aberg JA et al., Clin Infect Dis 2009 Sep 1; 49:651

SUMMARY AND COMMENT

DOT — Not Worth the Effort in Treatment-Naive HIV PatientsFree

• August 17, 2009
• Helmut Albrecht, MD

An open-label, randomized trial failed to show a lasting advantage for modified directly observed antiretroviral therapy over self-administered therapy.

• Reviewing:
• Gross R et al., Arch Intern Med 2009 Jul 13; 169:1224