HIV/AIDS Clinical Care: Archives

AIDS WATCH

CROI 2010 ReminderFree

• August 17, 2009

Abstracts for the 2010 Retrovirus Conference are due October 6, 2009. The conference will take place February 16–19, 2010, in San Francisco.

SUMMARY AND COMMENT

Non–AIDS-Defining Cancer Is More Common in HIV-Infected Than in HIV-Uninfected Men

• August 10, 2009
• Keith Henry, MD

In the U.S. VA Healthcare System, the incidence of non–AIDS-defining malignancies was 60% higher in HIV-infected patients than in matched HIV-uninfected patients.

• Reviewing:
• Bedimo RJ et al., J Acquir Immune Defic Syndr 2009 Jul 16

SUMMARY AND COMMENT

Impressive Results with Raltegravir in Treatment-Naive HIV Patients

• August 10, 2009
• Paul E. Sax, MD

Rates of virologic suppression were similar between raltegravir and efavirenz, but drug-related adverse events were less common with raltegravir.

• Reviewing:
• Lennox JL et al., Lancet 2009 Aug 3 Emery S and Winston A., Lancet 2009 Aug 3

SUMMARY AND COMMENT

Identifying Patients with Acute HIV Infection and Their Partners

• August 10, 2009
• Sonia Nagy Chimienti, MD

In North Carolina, a protocol for negative or indeterminate HIV-antibody results that involved nucleic acid amplification testing, confirmatory antibody testing, and follow-up interviews led to identification of newly infected partners of newly infected patients.

• Reviewing:
• Moore ZS et al., J Acquir Immune Defic Syndr 2009 Jun 26

LETTER TO READERS

Readers vs. Experts on the Question of Informed Consent and Possible Occupational Exposure to HIVFree

• August 10, 2009
• Paul E. Sax, MD

Experts say observe the law; readers say test the patient.

FEATURE

Monitoring HIV Patients' Kidney Function in Clinical Practice

• August 3, 2009
• Lynda Anne Szczech, MD, MSCE

What is known about kidney disease in other clinical contexts can help guide HIV care providers in monitoring the kidney function of their patients.

• Reviewing:
• Nickolas TL et al., Ann Intern Med 2008 Jun 3; 148:810 Paragas N et al., J Am Soc Nephrol 2009 Jul 23 Levey AS et al., Ann Intern Med 2009 May 5; 150:604 Cockcroft DW and Gault MH., Nephron 1976 Jan; 16:31 Levey AS et al., J Am Soc Nephrol 2000 ; 11:A0828 Ginsberg JM et al., N Engl J Med 1983 Dec 22; 309:1543 National Kidney Foundation., 2002 Szczech LA et al., AIDS 2007 May 11; 21:1003 Gupta SK et al., Clin Infect Dis 2005 Jun 1; 40:1559 Szczech LA et al., Kidney Int 2002 Jan; 61:195 Kopp JB et al., Nat Genet 2008 Oct; 40:1175 Reich HN et al., J Am Soc Nephrol 2007 Dec; 18:3177

SUMMARY AND COMMENT

Loss to Follow-Up Worsens Outcomes for HIV Patients, Even If They Return to CareFree

• August 3, 2009
• Rochelle P. Walensky, MD, MPH

Mortality risk was five times higher among HIV patients in northern France who returned to care after being lost to follow-up than among those who were never lost.

• Reviewing:
• Ndiaye B et al., AIDS 2009 Jun 15

SUMMARY AND COMMENT

Sex-Drug Use Increases HIV Risk for MSM

• July 27, 2009
• Keith Henry, MD

In a cohort of HIV-uninfected MSM, the use of poppers, stimulants, or erectile dysfunction drugs significantly increased the risk for acquiring HIV.

• Reviewing:
• Ostrow DG et al., J Acquir Immune Defic Syndr 2009 Jul; 51:349

ANTIRETROVIRAL ROUNDS

Stuck in the MiddleFree

• July 27, 2009

A clinician sustains a needlestick from a patient who refuses HIV testing. An HIV physician, an attorney, and an ethicist weigh provide weigh in on how best to manage.

SUMMARY AND COMMENT

Death from Non–AIDS-Related Causes: Another Risk of Immunodeficiency

• July 27, 2009
• Paul E. Sax, MD

Non–AIDS-related deaths accounted for more than half of all deaths in this cohort; the risk was reduced with a higher CD4-cell count.

• Reviewing:
• Marin B et al., AIDS 2009 Jun 30