Table 1. Primary Changes in the Recommendations:

  • The addition of statements concerning discontinuation of prophylaxis against specific OIs when the CD4+ T-lymphocyte count increases in response to HAART
  • New recommendations regarding human herpesvirus type 8 and hepatitis C virus
  • New recommendations concerning injection drug users
  • New recommendations about short-course chemoprophylaxis against tuberculosis in HIV-infected persons with positive tuberculin skin tests
  • Changes in secondary prophylaxis (chronic maintenance therapy) recommended to prevent the recurrence of Mycobacterium avium complex and cytomegalovirus disease
  • Caution against using fluconazole during pregnancy
  • Statements concerning the use of varicella and rotavirus vaccines among HIV-infected infants

From the 1999 USPH/IDSA guidelines for the prevention of opportunistic infections in person infected with human immunodeficiency virus. MMWR 1999 August 20; 48:RR-10, 2.