| Type of Condition |
Mechanism of Dysfunction |
Specific Disease and Drug |
|
| Vascular |
Arterial insufficiency |
Atherosclerotic peripheral vascular disease |
|
Veno-occlusive incompetence |
Diabetes mellitus |
| Neurologic |
Peripheral autonomic nervous system dysfunction neuronal lossTransection of nerve fibers during pelvic surgery |
|
Disordered neurotransmitter signaling |
Neurotransmitter agonist or antagonist antihypertensives, antidepressants |
|
Central nervous system dysfunction |
Stroke, multiple sclerosis |
| Endocrinologic |
Androgen deficiency |
Cirrhosis, alcoholism |
|
Testicular failure |
|
Hypothalamic-pituitary disease |
|
Prolactin excess |
|
Estrogen excess |
|
Inhibition of androgen action drugs |
Spironolactone, cimetidine, ketoconazole, megasterol |
|
Thyroid disease |
| Psychiatric |
Psychogenic inhibition of erotic response |
Depression, performance anxiety |
