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Guidelines for Preventing and Treating HIV-Related OIs

The National Institutes of Health, the CDC, and the HIV Medicine Association of the Infectious Diseases Society of America have published an update of their 2004 guidelines for the prevention and treatment of HIV-related opportunistic infections (OIs). These guidelines — which appear in the March 24, 2009, edition of MMWR — were released prepublication last summer and reviewed in the July 21, 2008, issue of Journal Watch AIDS Clinical Care. The only major change in the guidelines since their release last summer relates to the treatment of hepatitis B virus (HBV) coinfection. Consistent with HIV treatment guidelines from the U.S. Department of Health and Human Services, the OI treatment guidelines now recommend antiretroviral therapy (ART), regardless of CD4-cell count, for all coinfected patients who require HBV treatment; those who choose to defer ART should receive agents that are active against HBV only.

Published in AIDS Clinical Care March 30, 2009

Citation(s):

Centers for Disease Control and Prevention (CDC). Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: Recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. MMWR Morb Mortal Wkly Rep 2009 Mar 24; 58:1. (http://www.cdc.gov/mmwr/pdf/rr/rr58e324.pdf)

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